As a rule of thumb it's always seemed to me that consistency is a good thing.
The default Stinger Drain position is 'off', right? You need to manipulate the variable of wounds-on-your-champion to maximize the MacDirks. Not so for the DeathChasers, who come out of the box ready to rock and roll.
Use a low-life hero, you could have problems, use a higher-life hero, you are introducing other problems. There is more risk using the MacDirks, who I think perhaps compare more interestingly with the Greenscales.