I encourage anyone who reads this to google these comics for more clips (which so far seems to just be Necroblade
-- thx NB).
I've had the pleasure to work with Jeff a bunch of times. He's one of the smartest, wittiest comics in the biz. I believe this clip is from his second appearance on the Late Show with Letterman.
Jeff and Brett used to tour together quite often, as their acts work great together. Brett is a Tonight Show veteran. He has muscular dystrophy. Seinfeld said, "Brett Leake is one of the funniest comics in America."
Brett and Jeff both do squeaky clean comedy, but their material is so smart that you won't care.